Response Achieved in 8 out of 10 Immunotherapy Resistant Patients in First-in-Human Trial of Targeted Hyperthermia Therapy™
First-in-human study demonstrates meaningful clinical benefit in advanced, treatment-resistant melanoma. Sona’s CTAB-free, uniquely biocompatible gold nanorods delivered rapid tumor shrinkage with 6/10 biopsied tumors cleared of cancer within two weeks.
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Technology
Sona Nanotech’s mission is to transform cancer treatment using its patented, CTAB-free, uniquely biocompatible gold nanorod technology. Our Targeted Hyperthermia Therapy™ (THT) delivers controlled, localized heat directly into solid tumors, triggering apoptotic cancer cell death, revealing tumor antigens, and helping activate the immune system.
In 2025, THT demonstrated compelling early human efficacy in an immunotherapy-resistant melanoma patient study, achieving an 80% overall response rate and 60% complete responses, alongside a favourable safety and tolerability profile. These results build on years of translational research and reinforce Sona’s commitment to advancing safe, effective, and innovative therapies for patients with limited treatment options.
Sona Gold Nanorod ("GNR") Technology
Uniquely biocompatible, with the potential to revolutionize in-body medical applications.
Applications
Targeted Hyperthermia Therapy
Sona’s Targeted Hyperthermia Therapy for cancer aims to destroy tumors while doing little to no damage to healthy tissue.
Sona Gold Nanoparticles
Welcome to our collection of gold nanoparticles – tiny wonders with colossal potential. Gold nanoparticles are tiny pieces gold, typically ranging from 1 to 100 nanometers in size, making them invisible to the naked eye yet packed with remarkable properties. Renowned for their versatility and unique optical, electronic, and catalytic properties, gold nanoparticles are revolutionizing industries from medicine to electronics. Choose from our selection to help you in your discovery of extraordinary applications from cutting-edge medical diagnostics to advanced materials science. Unlock the power of gold nanoparticles and explore a world of endless possibilities.
Introducing Sona’s cutting-edge Gold Nanorods (GNRs), meticulously crafted using our patented proprietary techniques, completely free from CTAB.
Introducing Sona Gold – perfectly spherical gold nanoparticles, suspended in pure water, devoid of preservatives or suspension agents.
Scientific Study in Peer-reviewed Journal
Targeted intra-tumoral hyperthermia using uniquely biocompatible gold nanorods induces strong immunogenic cell death in two immunogenically ‘cold’ tumor models
Latest News Releases
Sona Nanotech Reports 80% Response Rate in First-In-Human THT Cancer Therapy Study
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